multigram ii (METTLER TOLEDO)
90
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METTLER TOLEDO
multigram ii
Multigram Ii, supplied by METTLER TOLEDO, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/multigram+ii/multigram+ii/us11325913-253-11-13
Average 90 stars, based on 1 article reviews
Multigram Ii, supplied by METTLER TOLEDO, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/multigram+ii/multigram+ii/us11325913-253-11-13
Average 90 stars, based on 1 article reviews
multigram ii - by Bioz Stars,
2026-10
90/100 stars
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Functional Assay:Article Title: Bicyclic compound and pharmaceutical use thereof Article Snippet: Trans-tert-butyl{[2-( Article Title: Nitrogen-containing five-membered heterocyclic compound Article Snippet: When the compound has a basic functional group and trifluoroacetic acid is used for this operation, a neutralization operation and the like may be performed to obtain a free form. preparative HPLC instrument: Gilson Inc., High-throughput purification system column: YMC Combiprep ODS-A S-5 μm, 20×50 mm solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=90/10), 1.20 min (SOLUTION A/SOLUTION B=90/10), 4.75 min (SOLUTION A/SOLUTION B=0/100), 7.30 min (SOLUTION A/SOLUTION B=0/100), 7.40 min (SOLUTION A/SOLUTION B=90/10), 7.50 min (SOLUTION A/SOLUTION B=90/10). flow rate: 25 ml/min, detection method: UV 220 nm or tool: Waters mass preparative system (UV Purification System) Column: Develosil ODS-UG-10 solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=95/5), 1.00 min (SOLUTION A/SOLUTION B=95/5), 2.00 min (SOLUTION A/SOLUTION B=80/20), 5.00 min (SOLUTION A/SOLUTION B=5/95), 5.10 min (SOLUTION A/SOLUTION B=0/100), 7.00 min (SOLUTION A/SOLUTION B=100/0) flow rate: 150 ml/min, detection: UV 220 nm In the following Article Title: Indole compound Article Snippet: In the present specification, the melting point refers to that measured using, for example, micromelting point measuring apparatus (Yanako, MP-500D or Buchi, B-545) or DSC (differential scanning calorimetry) device (SEIKO, EXSTAR6000) and the like. Neutralization:Article Title: Bicyclic compound and pharmaceutical use thereof Article Snippet: Trans-tert-butyl{[2-( Article Title: Nitrogen-containing five-membered heterocyclic compound Article Snippet: When the compound has a basic functional group and trifluoroacetic acid is used for this operation, a neutralization operation and the like may be performed to obtain a free form. preparative HPLC instrument: Gilson Inc., High-throughput purification system column: YMC Combiprep ODS-A S-5 μm, 20×50 mm solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=90/10), 1.20 min (SOLUTION A/SOLUTION B=90/10), 4.75 min (SOLUTION A/SOLUTION B=0/100), 7.30 min (SOLUTION A/SOLUTION B=0/100), 7.40 min (SOLUTION A/SOLUTION B=90/10), 7.50 min (SOLUTION A/SOLUTION B=90/10). flow rate: 25 ml/min, detection method: UV 220 nm or tool: Waters mass preparative system (UV Purification System) Column: Develosil ODS-UG-10 solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=95/5), 1.00 min (SOLUTION A/SOLUTION B=95/5), 2.00 min (SOLUTION A/SOLUTION B=80/20), 5.00 min (SOLUTION A/SOLUTION B=5/95), 5.10 min (SOLUTION A/SOLUTION B=0/100), 7.00 min (SOLUTION A/SOLUTION B=100/0) flow rate: 150 ml/min, detection: UV 220 nm In the following Article Title: Indole compound Article Snippet: In the present specification, the melting point refers to that measured using, for example, micromelting point measuring apparatus (Yanako, MP-500D or Buchi, B-545) or DSC (differential scanning calorimetry) device (SEIKO, EXSTAR6000) and the like. High Performance Liquid Chromatography:Article Title: Bicyclic compound and pharmaceutical use thereof Article Snippet: Trans-tert-butyl{[2-( Article Title: Nitrogen-containing five-membered heterocyclic compound Article Snippet: When the compound has a basic functional group and trifluoroacetic acid is used for this operation, a neutralization operation and the like may be performed to obtain a free form. preparative HPLC instrument: Gilson Inc., High-throughput purification system column: YMC Combiprep ODS-A S-5 μm, 20×50 mm solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=90/10), 1.20 min (SOLUTION A/SOLUTION B=90/10), 4.75 min (SOLUTION A/SOLUTION B=0/100), 7.30 min (SOLUTION A/SOLUTION B=0/100), 7.40 min (SOLUTION A/SOLUTION B=90/10), 7.50 min (SOLUTION A/SOLUTION B=90/10). flow rate: 25 ml/min, detection method: UV 220 nm or tool: Waters mass preparative system (UV Purification System) Column: Develosil ODS-UG-10 solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=95/5), 1.00 min (SOLUTION A/SOLUTION B=95/5), 2.00 min (SOLUTION A/SOLUTION B=80/20), 5.00 min (SOLUTION A/SOLUTION B=5/95), 5.10 min (SOLUTION A/SOLUTION B=0/100), 7.00 min (SOLUTION A/SOLUTION B=100/0) flow rate: 150 ml/min, detection: UV 220 nm In the following Article Title: Indole compound Article Snippet: In the present specification, the melting point refers to that measured using, for example, micromelting point measuring apparatus (Yanako, MP-500D or Buchi, B-545) or DSC (differential scanning calorimetry) device (SEIKO, EXSTAR6000) and the like. Purification:Article Title: Bicyclic compound and pharmaceutical use thereof Article Snippet: Trans-tert-butyl{[2-( Article Title: Nitrogen-containing five-membered heterocyclic compound Article Snippet: When the compound has a basic functional group and trifluoroacetic acid is used for this operation, a neutralization operation and the like may be performed to obtain a free form. preparative HPLC instrument: Gilson Inc., High-throughput purification system column: YMC Combiprep ODS-A S-5 μm, 20×50 mm solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=90/10), 1.20 min (SOLUTION A/SOLUTION B=90/10), 4.75 min (SOLUTION A/SOLUTION B=0/100), 7.30 min (SOLUTION A/SOLUTION B=0/100), 7.40 min (SOLUTION A/SOLUTION B=90/10), 7.50 min (SOLUTION A/SOLUTION B=90/10). flow rate: 25 ml/min, detection method: UV 220 nm or tool: Waters mass preparative system (UV Purification System) Column: Develosil ODS-UG-10 solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=95/5), 1.00 min (SOLUTION A/SOLUTION B=95/5), 2.00 min (SOLUTION A/SOLUTION B=80/20), 5.00 min (SOLUTION A/SOLUTION B=5/95), 5.10 min (SOLUTION A/SOLUTION B=0/100), 7.00 min (SOLUTION A/SOLUTION B=100/0) flow rate: 150 ml/min, detection: UV 220 nm In the following Article Title: Indole compound Article Snippet: In the present specification, the melting point refers to that measured using, for example, micromelting point measuring apparatus (Yanako, MP-500D or Buchi, B-545) or DSC (differential scanning calorimetry) device (SEIKO, EXSTAR6000) and the like. Solvent:Article Title: Bicyclic compound and pharmaceutical use thereof Article Snippet: Trans-tert-butyl{[2-( Article Title: Nitrogen-containing five-membered heterocyclic compound Article Snippet: When the compound has a basic functional group and trifluoroacetic acid is used for this operation, a neutralization operation and the like may be performed to obtain a free form. preparative HPLC instrument: Gilson Inc., High-throughput purification system column: YMC Combiprep ODS-A S-5 μm, 20×50 mm solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=90/10), 1.20 min (SOLUTION A/SOLUTION B=90/10), 4.75 min (SOLUTION A/SOLUTION B=0/100), 7.30 min (SOLUTION A/SOLUTION B=0/100), 7.40 min (SOLUTION A/SOLUTION B=90/10), 7.50 min (SOLUTION A/SOLUTION B=90/10). flow rate: 25 ml/min, detection method: UV 220 nm or tool: Waters mass preparative system (UV Purification System) Column: Develosil ODS-UG-10 solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=95/5), 1.00 min (SOLUTION A/SOLUTION B=95/5), 2.00 min (SOLUTION A/SOLUTION B=80/20), 5.00 min (SOLUTION A/SOLUTION B=5/95), 5.10 min (SOLUTION A/SOLUTION B=0/100), 7.00 min (SOLUTION A/SOLUTION B=100/0) flow rate: 150 ml/min, detection: UV 220 nm In the following Article Title: Indole compound Article Snippet: In the present specification, the melting point refers to that measured using, for example, micromelting point measuring apparatus (Yanako, MP-500D or Buchi, B-545) or DSC (differential scanning calorimetry) device (SEIKO, EXSTAR6000) and the like. Supercritical Fluid Chromatography:Article Title: Bicyclic compound and pharmaceutical use thereof Article Snippet: Trans-tert-butyl{[2-( Article Title: Nitrogen-containing five-membered heterocyclic compound Article Snippet: When the compound has a basic functional group and trifluoroacetic acid is used for this operation, a neutralization operation and the like may be performed to obtain a free form. preparative HPLC instrument: Gilson Inc., High-throughput purification system column: YMC Combiprep ODS-A S-5 μm, 20×50 mm solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=90/10), 1.20 min (SOLUTION A/SOLUTION B=90/10), 4.75 min (SOLUTION A/SOLUTION B=0/100), 7.30 min (SOLUTION A/SOLUTION B=0/100), 7.40 min (SOLUTION A/SOLUTION B=90/10), 7.50 min (SOLUTION A/SOLUTION B=90/10). flow rate: 25 ml/min, detection method: UV 220 nm or tool: Waters mass preparative system (UV Purification System) Column: Develosil ODS-UG-10 solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=95/5), 1.00 min (SOLUTION A/SOLUTION B=95/5), 2.00 min (SOLUTION A/SOLUTION B=80/20), 5.00 min (SOLUTION A/SOLUTION B=5/95), 5.10 min (SOLUTION A/SOLUTION B=0/100), 7.00 min (SOLUTION A/SOLUTION B=100/0) flow rate: 150 ml/min, detection: UV 220 nm In the following Article Title: Indole compound Article Snippet: In the present specification, the melting point refers to that measured using, for example, micromelting point measuring apparatus (Yanako, MP-500D or Buchi, B-545) or DSC (differential scanning calorimetry) device (SEIKO, EXSTAR6000) and the like. Concentration Assay:Article Title: Bicyclic compound and pharmaceutical use thereof Article Snippet: Trans-tert-butyl{[2-( Article Title: Nitrogen-containing five-membered heterocyclic compound Article Snippet: When the compound has a basic functional group and trifluoroacetic acid is used for this operation, a neutralization operation and the like may be performed to obtain a free form. preparative HPLC instrument: Gilson Inc., High-throughput purification system column: YMC Combiprep ODS-A S-5 μm, 20×50 mm solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=90/10), 1.20 min (SOLUTION A/SOLUTION B=90/10), 4.75 min (SOLUTION A/SOLUTION B=0/100), 7.30 min (SOLUTION A/SOLUTION B=0/100), 7.40 min (SOLUTION A/SOLUTION B=90/10), 7.50 min (SOLUTION A/SOLUTION B=90/10). flow rate: 25 ml/min, detection method: UV 220 nm or tool: Waters mass preparative system (UV Purification System) Column: Develosil ODS-UG-10 solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=95/5), 1.00 min (SOLUTION A/SOLUTION B=95/5), 2.00 min (SOLUTION A/SOLUTION B=80/20), 5.00 min (SOLUTION A/SOLUTION B=5/95), 5.10 min (SOLUTION A/SOLUTION B=0/100), 7.00 min (SOLUTION A/SOLUTION B=100/0) flow rate: 150 ml/min, detection: UV 220 nm In the following Article Title: Indole compound Article Snippet: In the present specification, the melting point refers to that measured using, for example, micromelting point measuring apparatus (Yanako, MP-500D or Buchi, B-545) or DSC (differential scanning calorimetry) device (SEIKO, EXSTAR6000) and the like. Injection:Article Title: Bicyclic compound and pharmaceutical use thereof Article Snippet: Trans-tert-butyl{[2-( Article Title: Nitrogen-containing five-membered heterocyclic compound Article Snippet: When the compound has a basic functional group and trifluoroacetic acid is used for this operation, a neutralization operation and the like may be performed to obtain a free form. preparative HPLC instrument: Gilson Inc., High-throughput purification system column: YMC Combiprep ODS-A S-5 μm, 20×50 mm solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=90/10), 1.20 min (SOLUTION A/SOLUTION B=90/10), 4.75 min (SOLUTION A/SOLUTION B=0/100), 7.30 min (SOLUTION A/SOLUTION B=0/100), 7.40 min (SOLUTION A/SOLUTION B=90/10), 7.50 min (SOLUTION A/SOLUTION B=90/10). flow rate: 25 ml/min, detection method: UV 220 nm or tool: Waters mass preparative system (UV Purification System) Column: Develosil ODS-UG-10 solvent: SOLUTION A; 0.1% trifluoroacetic acid-containing water, SOLUTION B; 0.1% trifluoroacetic acid-containing acetonitrile gradient cycle: 0.00 min (SOLUTION A/SOLUTION B=95/5), 1.00 min (SOLUTION A/SOLUTION B=95/5), 2.00 min (SOLUTION A/SOLUTION B=80/20), 5.00 min (SOLUTION A/SOLUTION B=5/95), 5.10 min (SOLUTION A/SOLUTION B=0/100), 7.00 min (SOLUTION A/SOLUTION B=100/0) flow rate: 150 ml/min, detection: UV 220 nm In the following Article Title: Indole compound Article Snippet: In the present specification, the melting point refers to that measured using, for example, micromelting point measuring apparatus (Yanako, MP-500D or Buchi, B-545) or DSC (differential scanning calorimetry) device (SEIKO, EXSTAR6000) and the like. |